Ready for unparalleled DNA transfection?
Perfectly engineered to enter mammalian cells, Nanocin PLASMID allows for highly efficacious DNA transfection in a range of cell types.

Its innovative design uses cutting-edge nanotechnology to counteract poor efficacy and toxicity often seen in the transfection process with other reagents.

Effectively non-toxic to mammalian cells, Nanocin PLASMID is safe to use in vivo, which means that you can translate results from lab to clinic with absolute confidence.

Discover how Nanocin PLASMID can improve the performance and integrity of your experiments.


  • Effectively non-toxic, allowing for repeated transfections with no need to replace media after transfection
  • GMP compliant and highly suited to clinical development
  • Rapid and streamlined protocol


More info

Combining DNA with the Nanocin PLASMID reagent results in rapid self-assembly of nanoparticles. This significantly enhances plasmid transfection into a wide range of mammalian cell types versus other leading reagents.

Compatible with in vivo applications, it can be used with even the most sensitive primary cells, unlike other commonly used reagents.

Nanocin PLASMID can also be used for repeated transfections whilst maintaining a healthy cell function, with no detrimental impact on the cells.

The rapid protocol for Nanocin PLASMID halves the time of a standard reagent protocol, reducing the process by several steps; saving you time in the lab and boosting long term yield.

Nanocin PLASMID is suitable for plasmid transfection in a wide range of cell types and cell lines, including:

  • HeLa
  • Neuro2a
  • HaCat
  • CHO
  • 293T
  • SAOS2
  • RPE-1
  • Neb1s
  • 1o Adipocytes



Test Specification
Appearance (Colour) Colourless
Appearance (Form) Solution
Volume (mL) 0.25, 0.5, 1.0, 10.0
Storage 2-8°C
Expiration Date Period 24 months
Trademark Nanocin™ is a trademark of Tecrea


Standard & Rapid Protocols

Plasmid transfection protocol


Material Safety Data Sheets



Is Nanocin PLASMID compatible with all types of plasmids?
Yes, you can use any plasmid with Nanocin PLASMID, although very large plasmids may require protocol optimisation. In some cases, adjusting the Nanocin PLASMID to plasmid ratio can improve efficiency with large plasmids.
Is Nanocin PLASMID compatible with all cell types?
Yes, but each cell line may require optimisation of transfection conditions. The Nanocin PLASMID protocol provides a convenient starting point, or you can contact us for further guidance.
Is Nanocin PLASMID compatible with linear or single stranded DNA?
Yes. Nanocin PLASMID will complex with all types of nucleic acids. Plasmid are the most common type of DNA used in delivery, but the protocol can be applied to any form of DNA as long as you know the concentration.
Is the buffer included important?
Yes; the buffer is optimised to improve efficiency and consistency.